Life purpose protects against dementia

According to a study published in the Archives of General Psychiatry, greater purpose in life y reduces the harmful senile brain changes which are associated with the development of Alzheimer’s disease.

Researchers of Rush University Medical Center examined data of 246 people without dementia who subsequently died and underwent brain autopsy.

The participants received annual clinical checks for about 10 years, including detailed cognitive testing and neurological exams.

Analyses showed that although plaques and tangles accumulated in most older people, those who had stronger motivations and a purpose in life were less likely to show mental decline.

The study defined a “purpose” as “the tendency to find meaning from life experience, to be intentional and focused.”

“Our study showed that people who reported greater purpose in life exhibited better cognition than those with less purpose in life even as plaques and tangles accumulated in their brains,” said senior author Patricia A. Boyle.

“These findings suggest that purpose in life protects against the harmful effects of plaques and tangles on memory and other thinking abilities. This is encouraging and suggests that engaging in meaningful and purposeful activities promotes cognitive health in old age.”

SJM/TE

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