Scientists Are Working on Vaccines that Spread Like a Disease. What Could Possibly Go Wrong?

May 2nd, 2021

You’ll love this:

Self-spreading vaccines have some of their roots in efforts to reduce pest populations. Australian researchers described a virally spread immunocontraception, which hijacked the immune systems of infected animals—in this case a non-native mouse species in Australia—and prevented them from fertilizing offspring.

Hmm.

Perhaps it will be used on two-legged pests.

Via: Bulletin of the Atomic Scientists:

Self-spreading vaccines could indeed entail serious risks, and the prospect of using them raises challenging questions.

Who decides, for instance, where and when a vaccine should be released? Once released, scientists will no longer be in control of the virus. It could mutate, as viruses naturally do. It may jump species. It will cross borders. There will be unexpected outcomes and unintended consequences. There always are.

Self-spreading vaccines are essentially genetically engineered viruses designed to move through populations in the same way as infectious diseases, but rather than causing disease, they confer protection. Built on the chassis of a benign virus, the vaccines have genetic material from a pathogen added to them that stimulates the creation of antibodies or white blood cells in “infected” hosts.

The principal security concern is that of dual-use. In essence, this means that the same research that is used to develop self-spreading vaccines to prevent disease, could also be used to deliberately cause harm. You could, for instance, engineer triggers into a virus that cause immune system failures in infected people or animals, a bit like HIV does naturally. Or you could create triggers in a virus that cause a harmful autoimmune response, where the body starts attacking its own healthy cells and tissues.

The bioweapon question. While researchers may intend to make self-spreading vaccines, others could repurpose their science and develop biological weapons. Such a self-spreading weapon may prove uncontrollable and irreversible.

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