Scientists Discover Lobotomy-Style Technique to Curbing Appetite



 Susanne.Posel-Headline.News.Official- lose.weight.oft.enzyme.turn.off.appetite_occupycorporatismSusanne Posel ,Chief Editor Occupy Corporatism | Media Spokesperson, HEALTH MAX Brands

 

Researchers from Johns Hopkins University (JHU) have discovered the coveted appetite switch in the brain that could help people lose weight.

According to this study , it is sugar in the blood that triggers that full feeling; however if that trigger does not work, the person could begin over eating.

While searching for a way to improve memory in mice, this team discovered that the enzyme OGT, involved in the metabolism, insulin and glucose, is also responsible for adding a derivative of glucose into proteins that control the appetite centers in the brain.

The authors said in a press release : “These mice don’t understand that they’ve had enough food, so they keep eating.”

And because the mice tripled their body weight in 3 weeks, and OGT is present in humans as well, the researchers concluded that their findings “may advance the search for drugs or other means of controlling appetites.”

While OGT looks like the culprit to obesity, last year the National Institutes of Health (NIH) funded a study on a single variation of the gene that controls brain – derived neurotropic factor (BDNF) which is believed to influence the development of obesity in children and adults.

This protein plays multiple roles in the brain and nervous system. At elevated levels, BDNF can make a person fell full.

Those with this genetic variation include African Americans and Hispanics; while Caucasians have the variation less frequently.

According to the study : “In African American adults, the C allele was associated with higher BMI and body fat percentage in those with CT or CC types … In the group of Hispanic children, the C allele (CT, CC types) was associated with a higher BMI score.”

The variation discovered in not rare, but a common mutation found among the general population. Because each human has 2 copies of the gene, inheriting one from each parent, the commonness of this issue is staggering.

More than 31,000 male and female participants were broken up into 4 groups. Their BDNF combination were analyzed for factors that would influence obesity such as the person’s body mass index (BMI) or their percentage of body fat.

For now, the Food and Drug Administration (FDA) has already approved the Maestro® System developed by EnteroMedics (EM), an implant treatment for obesity in adults.

For patients at least 70 – 80 pounds overweight, the implant is expected to be combined with “a supervised weight management program” to reduce obesity and help with heart-related issues.

The “pace-maker” device is primarily used for controlling “both hunger and fullness by intermittently blocking the primary nerve which regulates the digestive system” without the need for surgical restriction of the digestive system which lends to preventing the “absorption of nutrients and is completely reversible, allowing patients to lose weight without lifestyle compromises.”

Weight loss healthcare professionals assert this implant “adds a safe and effective new weapon to our armamentarium, offering the patient a treatment option that does not physically restrict or alter the anatomy, and is reversible.”

Scott Shikora, chief consulting medical officer for EM said their implant “offers an entirely new approach to the treatment of obesity by blocking signals along the nerves that connect the brain and stomach, VBLOC reduces feelings of hunger and promotes earlier feelings of fullness, which can help people with obesity reduce the number of calories consumed and promote safe, healthy and durable weight loss.”

Two years ago researchers at the University College London (UCL) discovered the FTO gene with the intent of developing pharmacological treatments for obesity.

Scientists in Japan first discovered ghrelin, which is manufactured in the stomach and gut in 1999. Research into how ghrelin affects and controls the body’s desire for food has found that this hormone decreases the body’s ability to burn fat which results in weight gain due to a slow metabolism.

Prior to the discovery of the FTO gene, researchers learned that there is connectivity within the brain between individuals and food addiction with regard to craving foods such as white bread and potatoes.

Source Article from http://feedproxy.google.com/~r/OccupyCorporatism/~3/Vx1Zwi8KOE0/

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