Ayahuasca and the Endocannabinoid System Scientists probe link between serotonin and cannabinoid signaling By Nate Seltenrich on June 22, 2022 Much as THC exerts the majority of its psychoactive effects through the CB1 cannabinoid receptor, the “classic” psychedelics – LSD, psilocybin, mescaline, and dimethyltryptamine (DMT) – are defined by activation of the serotonin 5-HT2A receptor. Widely distributed throughout the central nervous system, 5-HT2A …Source
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