Head Injury’s Location Key to Concussion Effects

FRIDAY, June 8 (HealthDay News) — Abnormalities that occur in various
areas of the brain and change over time may explain why concussions affect
people differently, according to a new study.

Patients can have widely varying responses to concussions. Most recover
with no lasting problems, but as many as 30 percent have permanent
effects, such as a personality change.

Previous research has shown there are differences between the brains of
people who have suffered concussions and people who haven’t, but it hadn’t
been determined if there were differences between the brains of concussion
patients.

“Most researchers have assumed that all people with concussions have
abnormalities in the same brain regions,” study lead author Dr. Michael
Lipton, associate director of the Gruss Magnetic Resonance Research Center
at Albert Einstein College of Medicine in New York City, said in a college
news release.

“But that doesn’t make sense, since it is more likely that different
areas would be affected in each person because of differences in anatomy,
vulnerability to injury and mechanism of injury,” said Lipton, who also is
medical director of MRI services at the Montefiore Medical Center in New
York City.

In this study, Lipton and his colleagues used a new MRI technique
called diffusion tensor imaging to scan the brains of 19 women and 15 men
who had concussions. The patients, aged 19 to 64, underwent a scan within
two weeks of their concussion and again three and six months later.

Using a special type of software to analyze the brain images, the
researchers found that concussion patients have unique patterns of
abnormalities in different brain regions and that the abnormalities change
over time.

It may be possible to use this new approach to assess concussion
patients, predict which head injuries are likely to have long-term
neurological effects and evaluate the effectiveness of treatments, Lipton
said.

The study was published online June 8 in the journal Brain Imaging
and Behavior
.

More information

The American Academy of Family Physicians has more about concussions.

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