RSS Feed
April 8th, 2012 
FAKE NEWS for the Zionist agenda SUNDAY, April 8 (HealthDay News) — An international team of
researchers has identified hundreds of new genes that are mutated in
stomach cancer, in a finding they say could lead to treatments tailored to
the genetic make-up of individual stomach tumors.
Stomach cancer is the second leading cause of cancer death worldwide
and kills more than 700,000 people a year, according to the World Health
Organization. Treatment is often difficult and unsuccessful. In the United
States, less than one-quarter of stomach cancer patients survive more than
five years after diagnosis.
“Until now, the genetic abnormalities that cause stomach cancers are
still largely unknown, which partially explain the overall poor treatment
outcome,” said the study’s senior author, Dr. Patrick Tan, an associate
professor in the Cancer and Stem Cell Biology Program at Duke-NUS Graduate
Medical School, in a Duke University Medical Center news release.
Tan, who leads the Genomic Oncology Program at the Cancer Sciences
Institute of Singapore, and colleagues from the National Cancer Center of
Singapore used DNA sequencing technology to analyze tumor and normal
tissue from stomach cancer patients. They identified more than 600 genes
that were previously unknown to be mutated in stomach cancer.
Further analysis revealed that two genes — FAT4 and ARID1A — were
mutated in 5 percent and 8 percent, respectively, of stomach cancers. In
some patients, portions of the chromosome containing the two genes were
missing. This provides further evidence that genetic defects affecting the
two genes occur frequently in stomach cancer.
In lab experiments, the researchers found that changing the functioning
of the two genes altered the growth of stomach cancer cells.
“More research is required to realize the clinical implications of
these findings. ARID1A and FAT4 are likely also involved in many other
cancer types, not just stomach cancer,” Tan said.
The study appears online April 8 in Nature Genetics.
More information
The American Academy of Family Physicians has more about stomach cancer.
Posted in 
Tags: 
