Smokers to get blood tests for lung cancer in mass NHS trial of procedure that detects disease up to FIVE years before symptoms appear

By
Claire Bates

06:10 EST, 23 March 2012

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06:10 EST, 23 March 2012

Risk factor: 85% of lung cancer patients are smokers

Risk factor: 85% of lung cancer patients are smokers

A life-saving blood test that predicts lung cancer up to five years before symptoms emerge is to be trialled on thousands of smokers by the NHS.

The test detects the killer condition at the earliest stage of development by detecting antibodies as soon as they are released by the body’s immune system to tackle early cancer cells.

Early treatment significantly increases a sufferer’s chances of survival. Between half and three-quarters of patients diagnosed at the earliest stage are still alive five years later. This drops to one per cent for the latest stage.

It has been used in the U.S for two years. Now NHS Scotland are to trial the procedure to see whether it would be cost-effective to use it for mass screening.

Around 40,000 people are diagnosed
with lung cancer in the UK each year while the disease causes 35,000
deaths.

Most patients (85 per cent) are only diagnosed when the disease
is advanced because it doesn’t cause noticeable symptoms until later on
when the chances of survival are low.

Sir Harry Burns, The Chief Medical Officer for Scotland, said: ‘By testing those at greatest risk of developing lung cancer, and diagnosing it at its earliest possible stage, we stand a better chance of being able to treat the cancer successfully.

‘This means patients can be treated when their general health is better and when less aggressive treatment may be required than if the cancer had spread.’

The trial, which will start later
this year, will include 10,000 high-risk smokers – those who have smoked
the equivalent of 20 cigarettes a day for 20 years. Smokers are 15 times more likely to die from lung cancer than non smokers.

The makers say the EarlyCDT Lung test can detect cancer cells before it is clearly visible on a CT scan

The makers say the EarlyCDT Lung test can detect cancer cells before it is clearly visible on a CT scan

Half will be given the EarlyCDT-Lung test and those who get a positive result will then have a CT scan to see if lung cancer is present. The other half will have the current standard of care.

The cost of care and survival rates for the two groups will then be compared. A recent study in the U.S of more than 50,000 smokers found it cut death rates by 20 per cent.

At present only 27 per cent of men and 30 per cent of women with lung cancer in the UK survive for at
least a year after being diagnosed. Just seven per cent of men and nine per cent of women will
survive for at least five years.

The test was created by Oncimmune Ltd, which is a spin out company from the University of Nottingham.

LUNG CANCER RATES IN 2008

Professor John Robertson, Chief Scientific Officer at Oncimmune said: ‘The test is highly reproducible and will I believe lead to significant improvement in prognosis for a substantial number of lung cancer sufferers.’

The test is based on the fact that as soon as cancer cells start to develop, and long before the patient notices any symptoms, the immune system starts to release antibodies, ‘soldier’ cells, that patrol the bloodstream trying to kill off malignant invaders.

The new lung cancer test, which has already been launched in the U.S., measures levels of six ­specific antibodies known to be linked to lung cancer.

The company, based at Nottingham Hospital, hope to release a breast cancer detection test next year that could detect signs of tumour development up to four years earlier than a mammogram. They are also looking at developing tests for prostate, colon and ovarian cancer.

Here’s what other readers have said. Why not add your thoughts,
or debate this issue live on our message boards.

The comments below have not been moderated.

Why should the NHS (TAX payers) foot the bill for people that are willingly risking cancer? – Lauren, Devon.
———————————
They don’t. Government tobacco revenue vastly exceeds the costs of treating smoking-related diseases. Smokers pay for their own treatment, and quite a bit more than that. I’m not sure who’s more addicted, smokers or the government.

Hold on a minute, a test to show lung cancer? MMMMM, They smoke, they know the risks yet they still smoke, do u really think that they will stop smokin if they are told they have cancer? Would be like shuttin the gate after the horse has boltd! Why should the NHS (TAX payers) foot the bill for people that are willingly risking cancer? It does not say that smokin kills on the packets for fun you know!!

What a waste of money. Anyone who smokes does not deserve health care.

Three men, all aged under 70 in my street, have all died recently from
various cancers.
None of them smoked, or drank to excess.
And as a non smoker, may I suggest the NHS finds more important
things to spend it’s money on. Like free parking at all Hospitals.
I couldn’t care less about those who smoke, it doesn’t bother me one bit.
I’m also a veggie, and I don’t mind if you eat meat.
The Nanny state, the bankrupt Nanny state let’s not forget, could start
minding it’s own business, then we’d all be better off.

the blood test would show if the patient had the lung cancer gene but it won’t mean they won’t get throat or mouth cancer or any other smoking related cancers?

If terminally ill people,including smokers, were to be given the ..RIGHT to DIE, with Dignity…many would not chose to linger in pain..on hospital beds…Most would chose to Check-Out…at minimal cost to the Anti-Smoking Brigade..!

Smoking related diseases cost the NHS about £5billion per annum…………… Cost of treating smokers on the NHS 2.7 billion..I must admit I am slightly puzzled. …………………… – I don’t smoke, but I’ll stick up for your rights to smoke., 23/3/2012 21:46……………………………..The 5 billion sum is smoking related disease treatment but just because it is smoking related you don’t have to smoke to get it. Take heart disease, it is a smoking related disease……………So smoking related diseases….You dont have to smoke to get them….You have definitely lost me there…. If you get a smoking related disease, it is not necessarliy because you smoke…..But surely if you do not smoke then that disease cannot be smoking related….Sorry way above my head.

After reading the title to this article who would had thought it would do such a good job at dividing the people, well done DM.

re: MARY POPPINS…So what do you mean..??? Smokers only get ..A Spoonfull of Sugar..????

So..before you anti-smoking Brigade..condone the actions of British Smokers.!! Why not dump on the Government for GIVING your hard earned money away..to a bunch of Far-Away places ,that don’t give a Monkeys if we ALL dropped dead..!! today..!

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