Machine Learning Algorithm Spots Depression in Speech Patterns


Researchers from the University of Southern California have developed a new machine learning tool capable of detecting certain speech-related diagnostic criteria in patients being evaluated for depression. Known as SimSensei, the tool listens to patient’s voices during diagnostic interviews for reductions in vowel expression characteristic of psychological and neurological disorders that may not be sufficiently clear to human interviewers. The idea is (of course) not to replace those interviewers, but to add additional objective weight to the diagnostic process.

The group’s work is described in the journal IEEE Transactions on Affective Computing.

Depression misdiagnosis is a huge problem in health care, particularly in cases in which a primary care doctor making (or not) the diagnosis. A 2009 meta-study covering some 50,000 patients found that docs were correctly identifying depression only about half the time, with the number of false positives outnumbering false negatives by a ratio of about three-to-one. That’s totally unacceptable.

But it’s also understandable. Doctors, especially general practitioners, will pretty much always overdiagnose an illness for two simple and related reasons: one, diagnosing an illness in error is almost always safer than not diagnosing an illness in error; two, eliminating with certainty the possibility of any single diagnosis requires more expertise/more confidence than otherwise. See also: overprescribing antibiotics.

A big part of the problem in diagnosing depression is that it’s a very heterogenous disease. It has many different causes and is expressed in many different ways. Figure that a primary care doctor is seeing maybe hundreds of patients in a week, for all manner of illness, and the challenge involved in extracting a psychiatric diagnosis from the vagaries of self-reported symptoms and interview-based observations is pretty clear. There exists a huge hole then for something like SimSensei.

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