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June 11th, 2012 
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Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study
The Lancet, Early Online Publication, 7 June 2012
doi:10.1016/S0140-6736(12)60815-0
Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study
Authors: Dr Mark S Pearce PhD a , Jane A Salotti PhD a, Mark P Little PhD c, Kieran McHugh FRCR d, Choonsik Lee PhD c, Kwang Pyo Kim PhD e, Nicola L Howe MSc a, Cecile M Ronckers PhD c f, Preetha Rajaraman PhD c, Alan W Craft MD b, Louise Parker PhD g, Amy Berrington de González DPhil c
Abstract: Interpretation
Use of CT scans in children to deliver cumulative doses of about 50 mGy might almost triple the risk of leukaemia and doses of about 60 mGy might triple the risk of brain cancer. Because these cancers are relatively rare, the cumulative absolute risks are small: in the 10 years after the first scan for patients younger than 10 years, one excess case of leukaemia and one excess case of brain tumour per 10 000 head CT scans is estimated to occur. Nevertheless, although clinical benefits should outweigh the small absolute risks, radiation doses from CT scans ought to be kept as low as possible and alternative procedures, which do not involve ionising radiation, should be considered if appropriate.
Tags: children maternity, disease medicine, pollution toxins
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