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December 18th, 2015 
Awake Goy 
Susanne Posel ,Chief Editor Occupy Corporatism | Co-Founder, Legacy Bio-Naturals
December 18, 2015
Researchers from Stanford University (SU) have published a study on the genetic clues that can point to answering the age old question: How do we live longer?
Humans who live to be 100 years old pique the interest of scientists who want to know if longevity is caused by avoidance of disease or if their genetic make-up gives them an anti-aging “secret”.
This study breaks the stereotype assumed by the scientific community that centenarians “have some anti-aging secret that shields them against the effects of aging” based on data showing that these people have “just as many genes that contribute to disease as those with more average life spans.”
Stuart Kim, professor of developmental biology and genetics at SU and lead author of the study, said “centenarians may have fewer of the genes that contribute to major chronic diseases”; however this study shows that they simply “don’t experience as much disease as people who are shorter-lived.”
Kim explained that comparing “the genomes of centenarians and people with average life spans” in order to “pick out the regions where the maps differ” is actually a red herring “because you search through hundreds of thousands, and now millions of variants, there is a lot of noise. So it makes it difficult to see the signal amidst all the noise.”
The team assumed “that disease genes can reduce the chances of someone reaching their 100s”, and armed with that filter, they discovered 5 regions of interest for explaining longevity.
• The gene connected to Alzheimer’s disease
• The area involved with heart disease
• Genes responsible for A-B-O blood type
• The HLA region involved with transplant organ rejection
• Disease avoidance
Kim said: “It seems intuitively obvious, that avoiding disease is part of the strategy of becoming a centenarian. But there is a really, really strong dogma in the field that there was no depletion of disease genes in centenarians, and that all of their survival benefit was coming from protection from anti-aging genes. I think they were wrong.”
Previously held understandings on what causes longevity has produced amazing discoveries into the process of extending the average human life span.
Earlier this year, researchers with the SU Baxter Laboratory for Stem Cell Biology (BLSCB) have found a viable way of producing anti-aging properties in cells producing a biological fountain of youth.
By modifying RNA, the researchers created “large numbers of cells for study or drug development.”
Skin cells with telomeres lengthened by the procedure were able to divide up to 40 more times than untreated cells. In essence, this technique could be used to stop aging which is caused by the shortening of telomeres over a lifetime.
Telomeres are the “are the caps at the end of each strand of DNA that protect our chromosomes, like the plastic tips at the end of shoelaces.”
New telomeres are 8,000-10,000 nucleotides long and shorten as cells divide. When they reach their maximum division, cells die which is the internal aging clock for humans and other life.
The injection of RNA to extend telomeres’ was successful. RNA which “contained the coding sequence for TERT, the active component of a naturally occurring enzyme called telomerase. Telomerase is expressed by stem cells, including those that give rise to sperm and egg cells, to ensure that the telomeres of these cells stay in tip-top shape for the next generation. Most other types of cells, however, express very low levels of telomerase.”
Researchers propose that “the development of telomere extension [could] improve cell therapies and to possibly treat disorders of accelerated aging in humans.”
Implications for diseases such as cardiovascular, diabetes, “conditions of aging” are now potentially in the realm of treatable with this discovery.
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