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December 31st, 2011 
FAKE NEWS for the Zionist agenda FRIDAY, Dec. 30 (HealthDay News) — Researchers have identified
three gene abnormalities that appear to raise the likelihood for
developing the thyroid cancer, with one in particular — the PTEN gene —
implicated in children’s risk for the disease.
Dr. Charis Eng, founding director of the Genomic Medicine Institute of
Cleveland Clinic’s Lerner Research Institute, said in a news release that
her team’s “investigation into the genetics behind thyroid disease raises
important details relevant to diagnosis and treatment. We hope to promote
the earliest diagnosis and most targeted treatment possible.”
The researchers unearthed the gene-cancer risk link by examining and
tracking roughly 3,000 patients, many of whom had already been diagnosed
with a different disease called Cowden syndrome.
The study, published in the Dec 1. issue of the Journal of Clinical
Endocrinology Metabolism, focused on mutations in three genes:
PTEN, SDH and KLLN. Because all work on distinct cell pathways, potential
treatments to reduce cancer risk would have to target each gene
individually.
Thyroid cancer has experienced the largest increase among both men and
women of all cancers, according to the Cleveland Clinic release.
PTEN is a tumor-suppressor gene that, when healthy, aids in cell growth
and division. Inherited PTEN mutations, however, impede the gene’s normal
function while spurring the growth of tumors. These abnormalities are
known to be present in about 80 percent of patients with Cowden syndrome,
who are considered at risk for developing breast and thyroid cancer.
The investigators concluded that mutations in the PTEN gene were indeed
associated with a rise in thyroid cancer risk, with some early indications
that mutations in the SDH and KLLN genes might also be implicated.
Children under the age of 18, however, seem to face a unique cancer
risk dynamic: While PTEN mutations were seen to elevate their risk for
thyroid cancer, SDH and KLLN abnormalities did not.
PTEN testing is already a staple in the world of genetic screening, the
release noted.
More information
For more on thyroid cancer, visit the U.S. National Library of Medicine.
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